Senior Scientist Research Computational Biology (ARIA)

Company: Amgen
Location: South San Francisco
Posted on: April 4, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Scientist Research Computational Biology (ARIA) What you will do Lets do this. Lets change the world. The ARIA Computational Biology team is seeking a talented and creative computational biologist to further our mission of serving patients by advancing and replenishing the Amgen therapeutic pipeline. In this role, you will apply your expertise in data science and mechanistic disease biology to accelerate the identification, prioritization, and validation of transformative therapeutic targets within a dynamic, cross-functional research environment. Focus areas include: Deriving biological insight from complex multi-modal omics and perturbation screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses. Conducting innovative, collaborative research in close partnership with Amgen therapeutic area scientists and our Discovery Sciences, Advanced Technologies, and AI (DATA) team, spanning discovery platforms, internal pipeline programs, and external partnerships. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a scientist with these qualifications. Basic Qualifications: PhD in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable] OR Masters degree in computational biology, bioinformatics, data science, or a related discipline and 3 years of relevant research experience OR Bachelors degree in computational biology, bioinformatics, data science, or a related discipline and 5 years of relevant research experience Preferred Qualifications: Strong background in cardiometabolic disease and/or immunology, including applications in the interpretation of single-cell data. Proficient in extracting actionable mechanistic insights from complex biological datasets through development and creative application of AI/ML-based analytical strategies. Strong programming skills (Python, R, Linux/Unix) and experience with cloud computing environments, HPC, and collaborative coding practices (e.g., Git). Track record of designing and executing creative and holistic computational strategies to address challenging research questions. Proven expertise in the analysis and interpretation of single-cell omics data. Excellent communication and presentation skills, with the ability to convey complex concepts to diverse audiences. Self-motivated, collaborative, and committed to continuous learning and growth. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Keywords: Amgen, Woodland , Senior Scientist Research Computational Biology (ARIA), Science, Research & Development , South San Francisco, California